Surface modification of biomaterials for conjugation with human fetal osteoblasts.
نویسندگان
چکیده
Surface functionalization of hydroxyapatite (HA) and beta-tricalcium phosphate (TCP) bioceramics with chemical ligands containing a pyrrogallol moiety was developed to improve the adhesion of bone cell precursors to the biomaterials. Fast and biocompatible copper-free click reaction with azido-modified human fetal osteoblasts resulted in improved cell binding to both HA and TCP bioceramics, opening the way for using this methodology in the preparation of cell-engineered bone implants.
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ورودعنوان ژورنال:
- Chimia
دوره 67 4 شماره
صفحات -
تاریخ انتشار 2013